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OCA Response Score (ORS)

Estimate the probability of response of patients with Primary Biliary Cholangitis treated with Obeticholic Acid.

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Enter variables at OCA therapy start

Alkaline Phosphatase (ALP)

Age at OCA start

Pruritus at OCA start

Cirrhosis

Total bilirubin

Alanine aminotransferase (ALT)

γ-glutamyltransferase (GGT)

OCA Response Score

Predicted probability of response to OCA:

According to Criteria 12 month 24 month
POISE -- --
ALP < 1.67 -- --
Normal Range -- --
POISE: ALP/ULN < 1.67 with a drop of at least 15%, and total bilirubin ≤ 1 mg/dL
Normal Range: ALP/ULN ≤ 1 and ALT/ULN ≤ 1 and total bilirubin ≤ 1 mg/dL

Disclaimer notice!

It is important to bear in mind that this is not a medical device and creators are not responsible for the use of the algorithm in a clinical setting